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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C9orf25 All Species: 26.06
Human Site: S126 Identified Species: 63.7
UniProt: Q8IW50 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IW50 NP_671735.1 185 20400 S126 F D M S R Y S S S G Y S S A E
Chimpanzee Pan troglodytes XP_001161024 185 20399 S126 F D M S R Y S S S G Y S S A E
Rhesus Macaque Macaca mulatta XP_001088997 270 28968 S211 F D M S R Y S S S G Y S S A E
Dog Lupus familis XP_531979 185 20381 S126 F D M S R Y S S S G Y S S A E
Cat Felis silvestris
Mouse Mus musculus Q9D772 157 17474 A104 S S S G Y S S A E Q I N Q D L
Rat Rattus norvegicus NP_001103086 157 17476 A104 S S S G Y S S A E Q I N Q D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511942 230 24741 S169 G E L E S R N S S G Y S S A E
Chicken Gallus gallus XP_001231783 185 20582 S126 F D M S R Y S S S G Y S S A E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DC60 186 20685 S127 F D M S R Y S S S G Y S S A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001178400 193 22137 R127 G Y S R L S T R D R E D E F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 68.1 100 N.A. 83.7 83.7 N.A. 36.5 95.1 N.A. 87 N.A. N.A. N.A. N.A. 39.3
Protein Similarity: 100 100 68.1 100 N.A. 84.3 83.7 N.A. 50 96.7 N.A. 91.9 N.A. N.A. N.A. N.A. 55.4
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 53.3 100 N.A. 100 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 20 20 N.A. 73.3 100 N.A. 100 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 20 0 0 0 0 0 70 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 60 0 0 0 0 0 0 10 0 0 10 0 20 10 % D
% Glu: 0 10 0 10 0 0 0 0 20 0 10 0 10 0 70 % E
% Phe: 60 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 20 0 0 20 0 0 0 0 0 70 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 20 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 20 % L
% Met: 0 0 60 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 20 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 20 0 0 20 0 0 % Q
% Arg: 0 0 0 10 60 10 0 10 0 10 0 0 0 0 0 % R
% Ser: 20 20 30 60 10 30 80 70 70 0 0 70 70 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 20 60 0 0 0 0 70 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _